Aortic aneurysm, hereditary thoracic panel

Aortic aneurysm,  hereditary thoracic panel
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Hereditary Thoracic Aortic Aneurym panel is a molecular diagnostic test that screens for relevant mutations in MYH11, ACTA2, TGFBR1, TGFBR2, FBN1, COL3A1, SMAD3, CBS, FBN2, SLC2A10, MYLK, and TGFB2 genes.

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Thoracic Aortic Aneurysm Disease (TAAD) is a genetically heterogeneous disorder, which primarily involves problems with the aorta, specifically the thoracic aorta. The major manifestations of TAAD include aortic dilatation, aortic aneurysms, aortic dissection, and aneurysms of the other arteries (i.e. abdominal, cerebral) . In Aortic aneurysm hereditary thoracic panel, MYH11, ACTA2, TGFBR1, TGFBR2, FBN1, COL3A1, SMAD3, CBS, FBN2, SLC2A10, MYLK, and TGFB2 genes will be analysed by PCR and next-generation sequencing.

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