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Catecholaminergic polymorphic ventricular tachycardia panel is a molecular diagnostic test to screen RYR2, CASQ2, and KCNJ2 genes.
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially fatal cardiac arrhythmia in individuals with a structurally normal heart. CPVT results from genetic mutations affecting cardiac calcium regulation. CPVT patients are sensitive to stress-induced releases of catecholamines that cause momentary dysfunction in cardiomyocytes.