Nutrigenomics: Unravel The Gene-Diet Connection

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Nutrigenomics-Unravel-The-Gene-Diet-Connection

“As far as your body’s cells are concerned, healthy diets are all essentially the same, resting on the same Four Pillars: meat on the bone, fermented and sprouted foods, organs and other “nasty bits,” and fresh, unadulterated plant and animal products.” ~ Catherine Shanahan.

A Quick Look Through:  

Latest advancements in science, technology and pollution have repeatedly moved us towards a healthier lifestyle. Also, the quest for finding advanced knowledge on good foods in the most recent times has drastically improved by research and healthcare professionals and nutritionists. Since time memorial, we are aware that food and genes play a huge role in our health condition. After the Human Genome Project (HGP) has completed in 2003, researchers started asking more about food and gene interactions and arrived at the concept of Nutrigenomics. Nutrigenomics relates to the use of life sciences like nutrition, biochemistry, proteomics, epigenomics etc to understand the molecular level interactions between genes and nutrients. Through Nutrigenomics, we will be able to create personalized diets with respect to an individual’s genotype. In one way, it will help us to reduce the symptoms of the already present diseases and help us avoid them in the near future. (Sales, NMR et al, 2014).

StrategicNutrition

(Source:http://jackyhattingh.co.za/blog/2018/06/29/nutrigenomics)

Basic Elements of Nutrigenomics:

The below discussed are the most common elements of nutritional genomics (Sharma, Praveen et al, 2017).

  • Food and diet is an important inclining factor for many diseases under individual conditions, like foods should contain less amounts of saturated fats in cardiovascular disease conditions.
  • Dietary establishments, foods and nutrients alter the structure of the gene, and eventually the human genome.
  • The genetic forms among individuals will tell the exact balance between health and disease. In the past, many genotypes were studied in various diseases that converse more vulnerability of the disease than others.
  • Genes that are solely dependent on dietary factors in its regulation will certainly play a role in progression and advancement of certain chronic diseases like obesity, cancer, type-2 diabetes and cardiovascular diseases.

Nutrigenomics and Personalized Diet:

The dietary status of humans will forever remain a big ask for the governments, healthcare departments, food industry and clinical sector. Frequent assessing the nutritional status to some extent will provide channels to acknowledge individual variations in dietary status, but requires the amalgamation of modern-day science and mercantile classes to put to practice. Of late, innovations in genomics and metabolomics are focused in bringing modern-day diagnostics to the impending health care practice, and engineered advancements are proactively developing channels to estimate biological fluids at affordable rates. It’s time the scientific community uses these tools to understand how these genetic and metabolic profiles vary in individuals with regards to their health. With accountable diagnostics playing positive role in food and dietary practice, it’s not so long to see the day where personalized foods allow individuals to attain better health and improve the quality of their lifestyle. (German, J Bruce et al, 2011).

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(Source:https://www.news-medical.net/news/20190528/Are-DNA-based-diets-and-personalized-medical-foods-the-future-for-weight-loss.aspx)

Know Yourself By Decoding Your Genes:

Through Nutrigenomics, you can get to know a plethora of health-related information that will assist you in knowing what works for your body and what doesn’t. For e.g. if you are intolerant to gluten, it will help you to consume those foods which will promote nutrients, and helps in managing the weight. By arriving at a particular diet that matches your genetic profile and needs of the body, you will find the right way to manage weight. For e.g. in the case of intolerance to gluten, you wouldn’t have known that feelings like bloating, tiredness and decrease in weight are due to a loaf of bread you ate. Nutrigenomics as a science will also help you in choosing foods, like decreasing intake of carbohydrates, taking foods rich in vitamins and minerals and eating healthy fats.  

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Food Allergy – The Genetics Behind It

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Importance and Advantages of Nutrigenomics:

One area where Nutrigenomics has a huge dictating role is in identifying optimal dietary and health conditions. You would have been hearing from many professionals that diet is the main factor in determining your fitness and health status. Irrespective of our physical activity, the food we take plays a key role in determining the weight and health including life-style diseases. Although we are aware of including a good number of fruits and vegetables in our diet, we should also remember a structured diet plan will go well in a long way. Most importantly, without knowing about your own genetic variants and present health status, you may not know the nutrients you lack or nutrients that you are consuming in excess.  

Nutrigenomics has the following advantages.
  • Dietary Reactions: Through Nutrigenomics, you can know the way your body reacts to the foods take and helps you in understanding any adverse reactions.  
  • Eating Behaviours: You can know the type of satiety your genetic makeup is inclined to; feeling full, longing for chocolates and delicacies, irritability to wheat products and many more.
  • Metabolic health factors: You can know how your diet affects your sugar levels in the blood, cholesterol levels and if you are at a danger of acquiring lifestyle diseases earlier than ever.
  • Nutritional Needs: You can know the type of vitamins and minerals in your foods to be optimized.

How Does Mapmygenome Help You?

With our proprietary test MyNutriGene, you can get an insight into your immunity, genetic predisposition to specific health conditions, and choose optimal health plans to pre-empt most of these risks. Our test will also help you learn about your metabolism, fat/carbohydrate response, food intolerance, and eating behavior. Through MyFitGene, you can truly personalize your training and diet while understanding the strengths and weaknesses of your body. Knowing what foods work for you will go a long way towards building better health. It’s time to Eat Wise, DNA Wise! To get this test done, write to info@mapmygenome.in or call us at 1800 102 4595.

 References:

  1. Evangelakou, Zoi et al. “Nutrigenomics as a tool to study the impact of diet on aging and age-related diseases: the Drosophila approach.” Genes & nutrition vol. 14 12. 2 May. 2019, doi: 10.1186/s12263-019-0638-6
  2. German, J Bruce et al. “Nutrigenomics and personalized diets: What will they mean for food?.” Annual review of food science and technology vol. 2 (2011): 97-123. doi:10.1146/annurev.food.102308.124147
  3. Ramos-Lopez, Omar, et al. “Guide for current nutrigenetic, nutrigenomic, and nutriepigenetic approaches for precision nutrition involving the prevention and management of chronic diseases associated with obesity.” Lifestyle Genomics 10.1-2 (2017): 43-62.
  4. Sales, N. M. R., P. B. Pelegrini, and M. C. Goersch. “Nutrigenomics: definitions and advances of this new science.”Journal of nutrition and metabolism 2014 (2014).
  5. Sharma, Praveen, and Shailendra Dwivedi. “Nutrigenomics and nutrigenetics: new insight in disease prevention and cure.” (2017): 371-373.
  6. Singh, Minati. “Mood, food, and obesity.” Frontiers in psychology vol. 5 925. 1 Sep. 2014, doi:10.3389/fpsyg.2014.00925

About the Author

Ravi Teja M

Ravi Mandapaka is a Content Writer at Mapmygenome. He has rich experience in researching and writing, having published articles in research journals in domains across life-sciences and literature. He is a reviewer for many international journals, Assistant Editor — International Journal of Home Science, and Editor — Ashwamegh, Indian Journal of English Literature. An aficionado of Field Hockey and Football, he is a regular columnist at The Sports Column and Sportskeeda. He has a  Master’s Degree in Food Science and Nutrition and decent experience in academia. He was part of the research team at ICMR National Institute of Nutrition. He is a member of the Nutrition Society of India (NSI) and Association of Food Scientists and Technologists (India) (AFSTI).

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