MTHFR gene polymorphisms
MTHFR gene codes for the enzyme methylenetetrahydrofolate reductase which is involved in the process of breaking down the amino acid homocysteine.
677T>C and 1298A>C mutations
MTHFR Ex5f, MTHFR Ex5r, MTHFR Ex8f, MTHFR Ex8r
- Molecular analysis : 2 ml of blood in an EDTA vacutainer (purple cap) collected aseptically.
- Prenatal Diagnosis : Chorionic villus sample (30-40 mg) or Amniotic fluid (20-30 ml ) or Purified DNA ( 2-3micro micrograms ) or Fetal chord blood sample ( 1-2 ml).
The samples may be sent at room temperature within 48 hrs from the sample collection time.
TRF + Form G + Form F + Clinical history*