- Spoligo TB and SmaRT TB
Most prevalent communicable infectious disease, a challenge in developing nations
A chronic inflammatory infectious disease caused by Mycobacterium tuberculosis in humans
Usually attacks the lungs, but can affect many other body parts
CE-IVD Spoligo TBTM
Principle of the Spoligotyping Method:
The typing method is based on DNA polymorphism present at one particular chromosomal locus, the "Direct Repeat" (DR) region, which is uniquely present in Mycobacterium tuberculosis complex bacteria.
Structure of the DR locus in the genome of M. tuberculosis H37Rv and M. bovis BCG-P3. The green rectangles depict the 36 bp Direct Repeat (DR).
SMARTTM TB Kit
Simple, one tube kit, a Real-time assay
Detects TB complex consisting of M. tuberculosis, M. bovis, M. africanum, M. canetti, M. microti, M. pinnipedii
Easy to prepare
A drop of master mix is added to DNA extracted from sample for TB test
Mixture is placed in machine for results
Works with a variety of machines
Easy to interpret:
Control curve (IPC) shows the test worked
TB Curve shows if TB is present
TBC-another confirmatory marker
Compatible with existing PCR technology
This Kit technology is compatible with industry standard Real-time run Polymerase Chain Reaction (PCR) equipments.
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