{"title":"Diagnostics","description":"\u003cp\u003e\u003cspan\u003eUnlock insights into your health with advanced \u003cstrong\u003ediagnostic genomic tests\u003c\/strong\u003e. Our precise and reliable diagnostics empower healthcare providers and individuals alike. Trust Mapmygenome™ for accurate and actionable results.\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"nipt-non-invasive-prenatal-testing","title":"NIPT (Non Invasive Prenatal Testing)","description":"\u003cp\u003e\u003cspan style=\"color: #000000;\" data-mce-style=\"color: #000000;\"\u003eNon-invasive prenatal screening (NIPS or NIPT), is the first-line screening test globally recommended for detecting \u003cb\u003ecommon chromosomal abnormalities \u0026amp; microdeletions in fetuses\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e from the cell-free DNA present in the maternal blood sample, passed from the placenta. On average ~10% of the circulating cell-free DNA is found in the maternal blood.\u003csup data-mce-fragment=\"1\"\u003e2\u003c\/sup\u003e \u003cstrong\u003eNIPT is a screening that can be done as early as at 10 weeks of gestation.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv data-content-type=\"row\" data-appearance=\"contained\" data-element=\"main\"\u003e\n\u003cdiv data-enable-parallax=\"0\" data-parallax-speed=\"0.5\" data-background-images=\"{}\" data-background-type=\"image\" data-video-loop=\"true\" data-video-play-only-visible=\"true\" data-video-lazy-load=\"true\" data-video-fallback-src=\"\" data-element=\"inner\" data-pb-style=\"K1HVHK9\"\u003e\n\u003cp data-content-type=\"html\" data-appearance=\"default\" data-element=\"main\" data-decoded=\"true\"\u003e\u003cem\u003e[Form-G Mandatory for this test. Form G and Test requisition form by clicking on download sample reports below]\u003c\/em\u003e\u003c\/p\u003e\n\u003cp data-content-type=\"html\" data-appearance=\"default\" data-element=\"main\" data-decoded=\"true\"\u003e\u003cem\u003e\u003ciframe title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/bgGU0OlY0T4?si=vk3ERL7eo_tRTlR8\u0026amp;start=30\" height=\"315\" width=\"560\" allowfullscreen=\"\" referrerpolicy=\"strict-origin-when-cross-origin\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" frameborder=\"0\"\u003e\u003c\/iframe\u003e\u003c\/em\u003e\u003cem\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cdiv data-content-type=\"html\" data-appearance=\"default\" data-element=\"main\" data-decoded=\"true\"\u003e\n\u003ch2\u003eWhy NIPT?\u003c\/h2\u003e\n\u003cp\u003eNIPT analyzes fetal chromosomal abnormalities using cell-free DNA in the mother's blood, eliminating the need for previously used invasive techniques such as Chorionic Villus sampling or amniocentesis, which carries a high risk of miscarriage. With its non-invasive nature, NIPT provides a solution and reports chromosomal abnormalities with high sensitivity.\u003c\/p\u003e\n\u003cp\u003eIt is important to note that NIPT is a screening test and cannot provide a final diagnosis based solely on its results. Nevertheless, NIPT demonstrates great sensitivity in detecting Down syndrome, capturing over 99% of cases\u003csup\u003e3\u003c\/sup\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv data-content-type=\"html\" data-appearance=\"default\" data-element=\"main\" data-decoded=\"true\"\u003e\n\u003ch2\u003eConditions screened for\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll autosomal chromosomal abnormalities including trisomies 13, 18, 21\u003c\/li\u003e\n\u003cli\u003eAll sex chromosomal abnormalities\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e*This test does not reveal the sex of the fetus in accordance with PCPNDT guidelines\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv data-content-type=\"row\" data-appearance=\"contained\" data-element=\"main\"\u003e\n\u003cdiv data-enable-parallax=\"0\" data-parallax-speed=\"0.5\" data-background-images=\"{}\" data-background-type=\"image\" data-video-loop=\"true\" data-video-play-only-visible=\"true\" data-video-lazy-load=\"true\" data-video-fallback-src=\"\" data-element=\"inner\" data-pb-style=\"BJ4HJ1A\"\u003e\n\u003cdiv data-content-type=\"html\" data-appearance=\"default\" data-element=\"main\" data-decoded=\"true\"\u003e\n\u003ch2\u003eClinical Utility\u003c\/h2\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"col-md-12\"\u003e\n\u003cul\u003e\n\u003cli\u003eNIPT can be performed as early as 10 weeks of gestation, allowing for earlier detection of chromosomal abnormalities compared to traditional screening methods.\u003c\/li\u003e\n\u003cli\u003eNIPT results can reduce anxiety and uncertainty for expectant parents by providing them with valuable information about their baby's health.\u003c\/li\u003e\n\u003cli\u003eReduced invasive tests by 94.8% \u0026amp; decrease in procedure-related miscarriages by 90.8%\u003cspan\u003e \u003c\/span\u003e\u003csup\u003e4\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv data-content-type=\"row\" data-appearance=\"contained\" data-element=\"main\"\u003e\n\u003cdiv data-enable-parallax=\"0\" data-parallax-speed=\"0.5\" data-background-images=\"{}\" data-background-type=\"image\" data-video-loop=\"true\" data-video-play-only-visible=\"true\" data-video-lazy-load=\"true\" data-video-fallback-src=\"\" data-element=\"inner\" data-pb-style=\"F6FIKOJ\"\u003e\n\u003cdiv data-content-type=\"html\" data-appearance=\"default\" data-element=\"main\" data-decoded=\"true\"\u003e\n\u003ch2\u003eWhen is NIPT recommended\u003c\/h2\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"col-md-8\"\u003e\n\u003cul\u003e\n\u003cli\u003eNIPT is generally recommended to all pregnant woman\u003c\/li\u003e\n\u003cli\u003eIf any soft marker tests (double, triple \u0026amp; quadruple marker) suggest for chromosomal abnormalities\u003c\/li\u003e\n\u003cli\u003eIf ultrasound High NT or absent nasal bone suggests for chromosomal abnormalities\u003c\/li\u003e\n\u003cli\u003eHistory of a prior pregnancy with a trisomy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv data-content-type=\"row\" data-appearance=\"contained\" data-element=\"main\"\u003e\n\u003cdiv data-enable-parallax=\"0\" data-parallax-speed=\"0.5\" data-background-images=\"{}\" data-background-type=\"image\" data-video-loop=\"true\" data-video-play-only-visible=\"true\" data-video-lazy-load=\"true\" data-video-fallback-src=\"\" data-element=\"inner\" data-pb-style=\"U0S08CM\"\u003e\n\u003cdiv data-content-type=\"html\" data-appearance=\"default\" data-element=\"main\" data-decoded=\"true\"\u003e\n\u003ch2\u003eMapmyGenome’s Offerings\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eIdentify risk for all chromosomal abnormalities including trisomy 13, 18, 21 and sex chromosomal aneuploidies.\u003c\/li\u003e\n\u003cli\u003eNon-invasive, safe and accurate\u003c\/li\u003e\n\u003cli\u003eHigh detection rate \u0026amp; Low failure rate\u003c\/li\u003e\n\u003cli\u003e\u0026gt;99% sensitivity and specificity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv data-content-type=\"html\" data-appearance=\"default\" data-element=\"main\" data-decoded=\"true\"\u003e\n\u003ch2\u003eBenefits\u003c\/h2\u003e\n\u003cp\u003e1. Analyzes fetal chromosomal abnormalities using cell-free DNA in the mother's blood, eliminating the need for invasive techniques which carry a high risk of miscarriage. \u003cbr\u003e\u003cbr\u003e2. NIPT chromosomal abnormalities, microdeletions and microduplications with high sensitivity. \u003cbr\u003e\u003cbr\u003e3. NIPT can be performed as early as 10 weeks of gestation, allowing for earlier detection of abnormalities compared to traditional screening methods. \u003cbr\u003e\u003cbr\u003e4. NIPT results can alleviate anxiety and uncertainty for expectant parents by providing them with valuable information about their baby's health.\u003c\/p\u003e\n\u003ch2\u003eTest Specification\u003c\/h2\u003e\n\u003ctable width=\"100%\" style=\"width: 100%;\" data-mce-fragment=\"1\" data-mce-style=\"width: 100%;\"\u003e\n\u003ctbody data-mce-fragment=\"1\"\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd data-mce-fragment=\"1\"\u003e\u003cstrong\u003eTechnique\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eNGS\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVariant Types\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCNVs\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTAT\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2 Weeks\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSample Requirements\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10 ml maternal blood in streck tube\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv data-content-type=\"html\" data-appearance=\"default\" data-element=\"main\" data-decoded=\"true\"\u003e\n\u003ch5\u003e\u003cbr\u003e\u003c\/h5\u003e\n\u003cp\u003eAs of October, 2020:The American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM) endorse NIPT as having the highest detection rate and lowest false positive rate for the common aneuploidies regardless of maternal age or baseline risk, of all screening options.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col type=\"1\"\u003e\n\u003cli\u003e\n\u003cp\u003eAmerican College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Obstetrics; Committee on Genetics; Society for Maternal-Fetal Medicine. Screening for Fetal Chromosomal Abnormalities: ACOG Practice Bulletin, Number 226. Am J Obstet Gynecol. 2020 Oct;136(4):e48-e69.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eHou, Y., Yang, J., Qi, Y. et al. Factors affecting cell-free DNA fetal fraction: statistical analysis of 13,661 maternal plasmas for non-invasive prenatal screening. Hum Genomics 13, 62 (2019).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSmith, Meagan et al. “A Case of False Negative NIPT for Down Syndrome-Lessons Learned.” Case reports in genetics vol. 2014 (2014): 823504. doi:10.1155\/2014\/823504\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKostenko, Emilia et al. “Clinical and Economic Impact of Adopting Noninvasive Prenatal Testing as a Primary Screening Method for Fetal Aneuploidies in the General Pregnancy Population.” Fetal diagnosis and therapy vol. 45,6 (2019): 413-423. doi:10.1159\/000491750\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"MapmyGenome","offers":[{"title":"Default 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undiagnosed illness\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul data-sourcepos=\"7:1-7:24\"\u003e\n\u003cli data-sourcepos=\"8:1-8:53\"\u003e\u003cstrong\u003eIdentify genetic factors in your family history\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul data-sourcepos=\"7:1-7:24\"\u003e\n\u003cli data-sourcepos=\"9:1-9:65\"\u003e\u003cstrong\u003eExplore personalized treatment options for genetic diseases\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul data-sourcepos=\"7:1-7:24\"\u003e\n\u003cli data-sourcepos=\"10:1-10:33\"\u003e\u003cstrong\u003eMake informed decisions about your health care\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-sourcepos=\"12:1-12:47\"\u003e\u003cstrong\u003eOur WES test provides exceptional coverage:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul data-sourcepos=\"14:1-15:76\"\u003e\n\u003cli data-sourcepos=\"14:1-14:110\"\u003e\n\u003cstrong\u003eAnalyze 21,000 protein-coding genes:\u003c\/strong\u003e\u003cspan\u003e We examine a vast majority of genes known to influence your health.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul data-sourcepos=\"14:1-15:76\"\u003e\n\u003cli data-sourcepos=\"15:1-15:76\"\u003e\n\u003cstrong\u003eDeep Sequencing (150X-180X):\u003c\/strong\u003e\u003cspan\u003e Gain a highly detailed picture of your exome for a more confident analysis.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-sourcepos=\"17:1-17:274\"\u003e\u003cstrong\u003eFor a comprehensive understanding of your genetic makeup and its impact on your health, pre-test genetic counseling is recommended.\u003c\/strong\u003e\u003cspan\u003e This personalized session will address your specific concerns about genetic testing,\u003c\/span\u003e\u003cspan\u003e explain the process,\u003c\/span\u003e\u003cspan\u003e and prepare you for the results.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-sourcepos=\"19:1-19:206\"\u003e\u003cstrong\u003eDon't settle for unanswered questions.\u003c\/strong\u003e\u003cspan\u003e Whole exome sequencing can be a powerful tool for unlocking the secrets of your health.\u003c\/span\u003e\u003cspan\u003e Take control of your health journey and explore the possibilities with WES.\u003c\/span\u003e\u003c\/p\u003e","brand":"MapmyGenome","offers":[{"title":"Without Raw Data","offer_id":52758212739351,"sku":"WES","price":26000.0,"currency_code":"INR","in_stock":true},{"title":"With Raw Data","offer_id":52758212772119,"sku":"WES-RDF_WES","price":31000.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/4223\/7207\/files\/WES.png?v=1714820784"},{"product_id":"whole-genome-sequencing","title":"Whole Genome Sequencing","description":"\u003cp\u003eCovering 95% to 98% of the genome, Whole Genome Sequencing offers a comprehensive view of your entire genome. 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